Chronic skin lichenification as unusual presentation of eosinophilic granulomatosis with polyangitis: case report and literature review
Authors
Francesco Sbrana; Barbara Loggini; Sara Galimberti; Michele Coceani; Marta Latorre; Veronica Seccia; Sara L'Abbate; Marta Mosca; Emilio Maria Pasanisi; Chiara Baldini;
Eosinophilic granulomatosis with polyangitis (EGPA) is an uncommon ANCA-associated systemic small-vessel necrotizing vasculitis. At times, EGPA presenting manifestations can be very different from the usually recognized disease patterns. We report a 52-year-old female patient with 3 years history of itching. During the time occurred a chronic skin lichenification on her legs and gradually developed a full-blown ANCA-MPO positive EGPA in combination with blood hypereosinophilia, eosinophilic vasculitis at skin biopsy, subclinical asthma and chronic rhinosinusitis.
