CheckAP: Prevalence of psoriatic arthritis (PsA) and performance evaluation of the EARP questionnaire in the population of Portuguese patients with psoriasis followed in a dermatology setting
Authors
Ana Rita Henriques; Fernando Pimentel-Santos; João Teles de Sousa; Leandro Silva; Laura Gago; Mariana Emília Santos; Ana Teodósio Chícaro; Margarida Lucas Rocha; Rita Pinheiro Torres; Bernardo Pimentel; Maria Helena Lourenço; Sandra Barão Neves; Ana Gusmão Palmeiro; Anabela Barcelos; Manuela Loureiro; Susana Silva; Elsa Vieira-Sousa; Carolina Ochôa Matos; Joana Ferro Antunes; Miguel Alpalhão; Nadine Correia Amaral; Alexandra Bernardo; Sofia Magina; Maria Seabra Rato; Pedro Ponte; Tiago Meirinhos; Tiago Torres; Marília Rodrigues; Martinha Henrique; Diogo Jesus; Alexandra Daniel; Luísa Brites; Patrícia Nero; Pedro Mendes-Bastos; Maria Pedro Valada; David Lopes; Rute Dinis de Sousa; Helena Canhão; Ana Maria Rodrigues;
Background: The percentage of Portuguese psoriasis patients with psoriatic arthritis is unknown but musculoskeletal complaints related to PsA affect up to a third of patients. Dermatologists can identify early PsA as skin symptoms often precede joint symptoms in 80% of patients. Efficient and easy to perform screening tools are needed to help dermatologists effectively discriminate between Pso and PsA patients. The present study aims to evaluate the prevalence of PsA in Pso patients followed in Portuguese dermatology clinics. Additionally, it aims to evaluate the EARP-PT performance (validity, sensitivity, specificity) and the best cut-off point to allow an early identification of PsA potential patients.
Methods: A multicentre national, cross-sectional, observational study with two independent assessments (dermatologist and rheumatologist), was performed. A PsA case was defined by a combination of expert opinion and classification criteria for psoriatic arthritis (CASPAR). The EARP-PT questionnaire screening performance was evaluated.
Results: Pso patients (n=172) were included with a mean age of 53.8+/-14.5 years, 53.5% were male with a mean time of diagnosis of 17.4+/-14.9 years. The prevalence of PsA in patients with Pso in our sample was 8.70% (95% CI: 4.8-14.2). The EARP-PT questionnaire displayed good internal consistency (Cronbach’s α=0.81) and, using a validated initial cut-off point of 3, demonstrated a sensitivity of 71.4% and specificity of 40.1%.
Conclusion: The estimated prevalence of PsA in a population of Pso patients followed in Portuguese dermatology clinics, is 8.7%. The EARP-PT questionnaire appears to be a useful tool for dermatologists in the early detection of PsA.
Ana Rita Henriques
CHRC
Fernando Pimentel-Santos
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
João Teles de Sousa
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Leandro Silva
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Laura Gago
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Mariana Emília Santos
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Ana Teodósio Chícaro
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Margarida Lucas Rocha
Centro Hospitalar e Universitário do Algarve, Serviço de Reumatologia, Faro, Portugal
Rita Pinheiro Torres
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Bernardo Pimentel
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Maria Helena Lourenço
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Sandra Barão Neves
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Ana Gusmão Palmeiro
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Anabela Barcelos
CHRC
Manuela Loureiro
Centro Hospitalar do Baixo Vouga
Susana Silva
Centro Hospitalar do Baixo Vouga
Elsa Vieira-Sousa
Rheumatology and Metabolic Bone Diseases Department
Carolina Ochôa Matos
Rheumatology and Metabolic Bone Diseases Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon Academic Medical Center
Joana Ferro Antunes
Centro Hospitalar e Universitário de Lisboa Norte
Miguel Alpalhão
Centro Hospitalar e Universitário de Lisboa Norte
Nadine Correia Amaral
Clínica Universitária de Reumatologia
Alexandra Bernardo
Centro Hospitalar Universitário de São João
Sofia Magina
Centro Hospitalar Universitário de São João
Maria Seabra Rato
Centro Hospitalar Universitário de São João
Pedro Ponte
Hospital dos Lusíadas
Tiago Meirinhos
Instituto Médico de Estudos Imunológicos
Tiago Torres
Instituto Médico de Estudos Imunológicos
Marília Rodrigues
Centro Hospitalar de Leiria, Hospital de Santo André
Martinha Henrique
Centro Hospitalar de Leiria, Hospital de Santo André
Diogo Jesus
Centro Hospitalar de Leiria, Hospital de Santo André
Alexandra Daniel
Centro Hospitalar de Leiria, Hospital de Santo André
Luísa Brites
Centro Hospitalar de Leiria, Hospital de Santo André
Patrícia Nero
Hospital CUF Descobertas
Pedro Mendes-Bastos
Hospital CUF Descobertas
Maria Pedro Valada
CHRC, NOVA Medical School
David Lopes
CHRC, NOVA Medical School
Rute Dinis de Sousa
CHRC, NOVA Medical School
Helena Canhão
CHRC, NOVA Medical School
Ana Maria Rodrigues
CHRC, NOVA Medical School
CHRC
Fernando Pimentel-Santos
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
João Teles de Sousa
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Leandro Silva
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Laura Gago
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Mariana Emília Santos
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Ana Teodósio Chícaro
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Margarida Lucas Rocha
Centro Hospitalar e Universitário do Algarve, Serviço de Reumatologia, Faro, Portugal
Rita Pinheiro Torres
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Bernardo Pimentel
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Maria Helena Lourenço
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Sandra Barão Neves
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Ana Gusmão Palmeiro
Centro Hospitalar Lisboa Ocidental, Hospital Egas Moniz
Anabela Barcelos
CHRC
Manuela Loureiro
Centro Hospitalar do Baixo Vouga
Susana Silva
Centro Hospitalar do Baixo Vouga
Elsa Vieira-Sousa
Rheumatology and Metabolic Bone Diseases Department
Carolina Ochôa Matos
Rheumatology and Metabolic Bone Diseases Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon Academic Medical Center
Joana Ferro Antunes
Centro Hospitalar e Universitário de Lisboa Norte
Miguel Alpalhão
Centro Hospitalar e Universitário de Lisboa Norte
Nadine Correia Amaral
Clínica Universitária de Reumatologia
Alexandra Bernardo
Centro Hospitalar Universitário de São João
Sofia Magina
Centro Hospitalar Universitário de São João
Maria Seabra Rato
Centro Hospitalar Universitário de São João
Pedro Ponte
Hospital dos Lusíadas
Tiago Meirinhos
Instituto Médico de Estudos Imunológicos
Tiago Torres
Instituto Médico de Estudos Imunológicos
Marília Rodrigues
Centro Hospitalar de Leiria, Hospital de Santo André
Martinha Henrique
Centro Hospitalar de Leiria, Hospital de Santo André
Diogo Jesus
Centro Hospitalar de Leiria, Hospital de Santo André
Alexandra Daniel
Centro Hospitalar de Leiria, Hospital de Santo André
Luísa Brites
Centro Hospitalar de Leiria, Hospital de Santo André
Patrícia Nero
Hospital CUF Descobertas
Pedro Mendes-Bastos
Hospital CUF Descobertas
Maria Pedro Valada
CHRC, NOVA Medical School
David Lopes
CHRC, NOVA Medical School
Rute Dinis de Sousa
CHRC, NOVA Medical School
Helena Canhão
CHRC, NOVA Medical School
Ana Maria Rodrigues
CHRC, NOVA Medical School
